Photographer James Nachtwey traveled across America to capture the devastating toll of opioid addiction.

The opioid crisis is the worst addiction epidemic in American history. Drug overdoses kill more than 64,000 people per year, and the nation’s life expectancy has fallen for two years in a row. But there is a key part of the story that statistics can’t tell. Over the last year, photographer James Nachtwey set out to document the opioid crisis in America through the people on its front lines. Alongside TIME’s deputy director of photography, Paul Moakley, the pair traveled the country gathering stories from users, families, first responders and others at the heart of the epidemic. Here, Nachtwey’s images are paired with quotes from Moakley’s interviews, which have been edited. The voices are a mix of people in the photos and others who are connected to them. The Opioid Diaries is a visual record of a national emergency—and it demands our urgent attention.

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VIEW THE FULL ARTICLE & PHOTOS: time.com/james-nachtwey-opioid-addiction-america/